17/03/2020

The Influence of Compressibility on the Dynamics of Encapsulated Microbubbles

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  • ORGANISATION NAME
    Cardiff University
  • ORGANISATION COUNTRY
    United Kingdom
  • DEADLINE DESCRIPTION
    Open
  • RESEARCH FIELD
    Formal sciences

Outline

Thin-shell encapsulated microbubbles (EMBs) are gas-filled microbubbles encased in a stiff albumin or flexible lipid shell. They have been shown to improve the performance of biomedical procedures such as ultrasound contrast imaging, targeted drug delivery and sonoporation.

The viscoelastic fluid will be modelled using models such as the Oldroyd B model while the properties of the shell are accounted for through the dynamic boundary condition at the bubble surface.

An interdisciplinary approach combining models for cell mechanics with bubble dynamics will provide insights into the deformation of cellular entities subject to cavitation flow and to enhance drug delivery via coated microbubbles. Ultrasonic cavitation is one of the most effective cleaning agents. For example, it is used to clean and to disinfect surgical instruments in hospitals. There is a wide range of other biomedical applications that will benefit from the computational models developed in this project.

What is funded

Self-funded students only.

How to Apply

Applicants should submit an application for postgraduate study via the online application service http://www.cardiff.ac.uk/study/postgraduate/research/programmes/programme/mathematics

In the research proposal section of your application, please specify the project title and supervisors of this project and copy the project description in the text box provided.

In the funding section, please select the ’self -funding’ option.

We are interested in pursuing this project and welcome applications if you are self-funded or have funding from other sources, including government sponsorships or your employer.

Disclaimer:

The responsibility for the funding offers published on this website, including the funding description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.